§ 161 Fifth Edition
When I here limit the so-called homoeopathic aggravation, or rather the primary action of the homoeopathic medicine that seems to increase somewhat the symptoms of the original disease, to the first or few hours, this is certainly true with respect to diseases of a more acute character and of recent origin, but where medicines of long action have to combat a malady of, considerable or of very long standing, where one dose, consequently, must continue to act for many days, we then occasionally see, during the first six, eight or ten days, the occurrence of some such primary actions, of the medicine, some such apparent increase of the symptoms of the original disease (lasting for one or several hours), while in the intervening hours amelioration of the whole malady is perceptible. After the lapse of these few days the amelioration resulting from such primary action of the medicine proceeds almost uninterruptedly for several days longer.
§ 161 Sixth Edition
When I here limit the so-called homoeopathic aggravation, or rather the primary action of the homoeopathic medicine that seems to increase somewhat the symptoms of the original disease, to the first or few hours, this is certainly true with respect to diseases of a more acute character and of recent origin, but where medicines of long action have to combat a malady of, considerable or of very long standing, where no such apparent increase of the original disease ought to appear during treatment and it does not so appear if the accurately chosen medicine was given in proper small, gradually higher doses, each somewhat modified with renewed dynamization (§ 247). Such increase of the original symptoms of a chronic disease can appear only at the end of treatment when the cure is almost or quite finished.