§ 199
If the remedy perfectly homoeopathic to the disease had not yet been discovered1 at the time when the local symptoms were destroyed by a corrosive or desiccative external remedy or by the knife, then the case becomes much more difficult on account of the too indefinite (uncharacteristic) and inconstant appearance of the remaining symptoms; for what might have contributed most to determine the selection of the most suitable remedy, and its internal employment until the disease should have been completely annihilated, namely, the external principal symptom, has been removed from our observation.
1 As was the case before my time with the remedies for the condylomatous disease (and the antipsoric medicines).