Aphorism 48

§ 48

Neither in the course of nature, as we see from all the above examples, nor by the physician’s art, can an existing affection or malady in any one instance be removed by a dissimilar morbific agent, be it ever so strong, but solely by one that is similar in symptoms and is somewhat stronger, according to eternal, irrevocable laws of nature, which have not hitherto been recognized.

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Organon of medicine